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Autoimmune Liver Disease(ALD) Test Kit

short description:

Autoimmune liver diseases (ALD) include autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), which occurs in all ages and affect women more commonly than men. Clinical presentation may be an acute hepatitis up to fulminant liver failure, but can also be asymptomatic.


  • FOB Price: US $0.5 - 9,999 / Piece
  • Min.Order Quantity: 100 Piece/Pieces
  • Supply Ability: 10000 Piece/Pieces per Month
  • Product Detail

    Product Tags

    Chemiluminescent Solution(Autoimmune Diseases)

    Series

    Product Name

    Abbr

    Autoimmune Encephalitis Antibodies Profile

    Anti-NMDAR Antibody

    NMDAR

    Anti-AMPA1 Antibody

    AMPA1

    Anti-AMPA2 Antibody

    AMPA2

    Anti-LGI1 Antibody

    LGI1

    Anti-CASPR2 Antibody

    CASPR2

    Anti-GABARB Antibody

    GABABR

    Anti-IgLON5 Antibody

    IgLON5

    Anti-DPPX Antibody

    DPPX

    NMDAR is a subtype of ionotropic glutamate receptor and its molecular structure is complex. The mainly clinical manifestations are psychiatric and behavioral abnormalities, seizures, and near event memory impairment and other multifocal or diffuse brain damage.

    AMPA receptors mediate fast excitatory synaptic transmission in the central nervous system (CNS) and are involved in regulating learning and memory activity. Anti AMPAR encephalitis occurs with typical limbic encephalitis manifestations including subacute unconsciousness, depression, irritability, near memory loss and seizures with medial temporal lobe dysfunction, but generally without clinical manifestations of progressive movement disorder, central hypoventilation and autonomic dysfunction.

    LGI1 is a secreted protein interacting with two kinds of epilepsy related proteins

    CASPR2 is a member of the axon protein superfamily. Patients with positive anti CASPR2 antibody in serum or CSF can present with encephalitis, peripheral nerve hyperexcitability or Morvan’s syndrome.

    GABABR belongs to G protein coupled receptor, widely distributed in the brain and spinal cord, especially in hippocampus, thalamus and cerebellum. Patients can present with typical limbic encephalitis with early predominant seizures, as well as memory and behavioural abnormalities that can be very easily misdiagnosed as viral encephalitis.

    DPPX related encephalitis is a relatively rare AE in the clinic, which has an insidious onset and mostly a chronic course. The later clinical manifestations are diverse and lack specificity, such as CNS hyperexcitability, sensory disturbance, autonomic dysfunction, psychopsychiatric disturbance and cognitive dysfunction, and a small proportion of patients present with weakness and pain in both lower limbs with falls.

    C-luminary is a leading Autoimmune Encephalitis Antibodies Profile testing solutions provider, by utilizing the latest chemiluminese technology, that offers a good sensitivity, large linear range, and great stability,Quantitive testing available for some of the crucial test items.

     


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