Thyroid Function Chemiluminescense Immunoassay Kit

The thyroid is one of the most important endocrine glands in the human body, and thyroid function is of great significance to our health. Thyroid dysfunction or abnormal hormone secretion can cause abnormal symptoms in the human nervous system, circulatory system, digestive system and other systems, and can even be life-threatening. Clinically, thyroid function test indicators include thyroid stimulating hormone (TSH), triiodothyronine (T3) and free T3 (FT3), trans-triiodothyronine (rT3), thyroxine (T4) and free T4 ( FT4), thyrotropin receptor antibody (TRAb), thyroglobulin (Tg), thyroglobulin antibody (TgAb), anti-thyroid peroxidase antibody (TPOAb)and other serological indicators .

Thyroid-stimulating hormone is one of the hormones secreted by the anterior pituitary. Its main function is to control and regulate the activity of the thyroid gland. TSH is mainly responsible for regulating the proliferation of thyroid cells, the blood supply of the thyroid gland, and the synthesis and secretion of thyroid hormones. Thyroid-stimulating hormone level in blood is one of the important indicators for the diagnosis and treatment of hyperthyroidism and hypothyroidism as well as the study of hypothalamic-pituitary-thyroid axis. triiodothyronine, free triiodothyronine, trans-triiodothyronine, Thyroxine, free thyroxine are secreted by the thyroid, and their concentration is used to aid in the evaluation of thyroid function and is a specific diagnostic index for hyperthyroidism and hypothyroidism. Anti-thyroid peroxidase antibody, anti-thyroglobulin antibody and Thyroid microsomal antibody are common autoantibodies in the serum of patients with autoimmune thyroid disease. Thyroglobulin is the target antigen of anti-thyroglobulin antibodies, Anti-thyroid peroxidase antibodies and Thyroid microsomal antibody are thyroid peroxidase specific autoantibodies. Thyroid autoimmune disease is an important cause of underlying hypothyroidism and hyperthyroidism, and it often occurs in genetically predisposed individuals. Thyroid-stimulating hormone receptor antibody (TRAb), also known as membrane receptor antibody, is an antibody that directly acts on the TSH receptor on the thyroid cell membrane. It is of great significance for the diagnosis, treatment and prognosis of Graves disease. The vast majority of thyroglobulin is a macromolecular glycoprotein synthesized by thyroid cells and released into the thyroid follicle remnant cavity, and is the precursor of thyroid hormone molecules. A small amount of TG can be detected in the serum of normal healthy people. When the thyroid gland is stimulated by disease factors, part of TG is released into the blood circulation, so that the concentration in the blood circulation is significantly higher than that in the normal state. Therefore, the level of TG in the blood circulation can reflect the size of differentiated thyroid tissue, physical damage or inflammation of the thyroid gland, and the degree of TSH stimulation.