Volume : 50 µg
Clone Number :
Aliases : Binding peptide antibody; BP antibody; Haptoglobin alpha chain antibody; Haptoglobin alpha(1S) beta antibody; Haptoglobin alpha(2FS) beta antibody; Haptoglobin beta chain antibody; Haptoglobin, alpha polypeptide antibody; Haptoglobin, beta polypeptide antibody; HP antibody; HP2 ALPHA2 antibody; HP2ALPHA2 antibody; HPA1S antibody; HPT antibody; HPT_HUMAN antibody; MGC111141 antibody; Zon µLin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P00738
Immunogen : Recombinant Human Haptoglobin protein (19-406AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : As a res µLt of hemolysis, hemoglobin is found to accum µLate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in mod µLating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells thro µgh an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zon µLin, plays a role in intestinal permeability, allowing intercell µLar tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HP
Research Areas : Cardiovasc µLar